Hegde book of dravyaguna part 2 read online

Objectives: To study the anti-inflammatory activity of Hyoscine butyl bromide in acute and sub-acute animal models.

Medical College, Mysore, Karnataka, India Conclusion: The test compounds have the potential to be used as safer alternatives to the currently used NSAIDs and can be explored further with more detailed study.Įvaluation of Anti-inflammatory Activity of Hyoscine Butyl Bromide in Albino Wistar Ratsĭepartment of Pharmacology, J.S.S. Results: Drugs under study (A, B and C) exhibited dose dependent anti-inflammatory activity and no ulcerogenic potential however test compound A exhibited highest activity among the analysed analogues and was comparable to standard drug i.e. The ulcerogenic index was calculated by removing the stomachs of rats dosed for 7 days and examining the mucosa for lesions. Effect on chronic inflammation was evaluated by implanting 10 mg sterile cotton pellets subcutaneously into the groin region of female Wistar rats and determining % decrease in weight of the cotton. In-vivo anti-inflammatory activity was evaluated by the following Methods: Female Wistar rats were administered 0.1 mL of 1% carrageenan in the sub-plantar portion of hind paw to induce edema and then the present inhibition of edema calculated to study effect of drugs on acute inflammation. Proteinase inhibitory activity was studied by trypsin-casein and recording absorbance using spectrophotometer. Membrane stabilization activity was on human RBCs by recording absorbance using spectrophotometer.

Materials and Methods: In-vitro anti-inflammatory activity was evaluated by the given Methods: Inhibition of protein denaturation was studied using 5% w/v bovine serum albumin and recording absorbance using spectrophotometer. Objectives: The Objectives of the study was to evaluate the anti-inflammatory activity and ulcerogenic potential of 1, 3, 4-oxadiazole derivatives.

College of Pharmacy, Chamber, Mumbai, Maharashtra, India Study of Anti-inflammatory and Ulcerogenic Potential of some Structurally Similar 1, 3, 4-oxadiazole Analoguesīichave A, Aggarwal A, Shinde PK, Pimple Sĭepartment of Pharmacology, V.E.S.

Hegde book of dravyaguna part 2 read online